北京航空航天大學(xué)

主要研究方向及特色：研究方向：生物材料、生物力學(xué)研究特色：1.生物力學(xué)領(lǐng)域：應(yīng)力環(huán)境對(duì)骨基質(zhì)生物礦化的影響及機(jī)理研究2.生物力學(xué)領(lǐng)域：失重性骨丟失的力生物學(xué)機(jī)理及其對(duì)抗措施3.生物材料領(lǐng)域：生長(zhǎng)因子的控制釋放和生物活性人工骨修復(fù)材料的研究4.生物材料領(lǐng)域：三維打�。�3Dprinting）構(gòu)建生物材料支架

電子信箱：nxf@buaa.edu.cn

辦公電話：010-82338755

辦公地點(diǎn)：北京航空航天大學(xué)生物與醫(yī)學(xué)工程學(xué)院415房間

通信地址：北京市海淀區(qū)學(xué)院路37號(hào)

個(gè)人簡(jiǎn)介：

1.個(gè)人情況簡(jiǎn)介

牛旭鋒，男，1979年生，工學(xué)博士，副教授，博士生導(dǎo)師�，F(xiàn)就職于北京航空航天大學(xué)生物與醫(yī)學(xué)工程學(xué)院，主要從事生物材料和生物力學(xué)領(lǐng)域的研究。2012年入選北京航空航天大學(xué)“藍(lán)天新星計(jì)劃”，2009年入選北京航空航天大學(xué)“藍(lán)天新秀計(jì)劃”，博士學(xué)位論文入選2007年度重慶大學(xué)“優(yōu)秀博士學(xué)位論文獎(jiǎng)”（論文題目：聚（D,L-乳酸）基仿生細(xì)胞外基質(zhì)的骨組織工程基質(zhì)材料研究）。正在主持1項(xiàng)國(guó)家自然科學(xué)基金面上項(xiàng)目、1項(xiàng)國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目子課題、1項(xiàng)國(guó)家科技支撐計(jì)劃項(xiàng)目子課題、以及1項(xiàng)教育部基本科研業(yè)務(wù)費(fèi)。已主持完成1項(xiàng)國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目和1項(xiàng)中國(guó)博士后科學(xué)基金項(xiàng)目，曾參與多項(xiàng)國(guó)家科技支撐計(jì)劃和國(guó)家863計(jì)劃項(xiàng)目。到目前為止共發(fā)表SCI論文20余篇，SCI數(shù)據(jù)庫(kù)中統(tǒng)計(jì)的總引用頻次達(dá)150次。以第一發(fā)明人申請(qǐng)國(guó)家發(fā)明專(zhuān)利3項(xiàng)，獲授權(quán)專(zhuān)利1項(xiàng)。擔(dān)任“中國(guó)生物醫(yī)學(xué)工程學(xué)會(huì)”會(huì)員、“中國(guó)生物材料學(xué)會(huì)”會(huì)員、以及“世界華人生物醫(yī)學(xué)工程協(xié)會(huì)”會(huì)員，兼任Nanotechnology、Artificial Organs、Journal of Biomedical Materials、Biofabrication、Polymer International、Journal of Materials Science、International Journal of Pharmaceutics、Biomedical Materials、Materials Science and Engineering、Colloids and Surfaces、Frontiers of Materials Science等SCI雜志的特約審稿人。

2.教學(xué)情況

承擔(dān)的研究生課程：《生物醫(yī)學(xué)工程前沿》、《生物醫(yī)學(xué)工程研究方法》、《生物醫(yī)學(xué)儀器分析》、《科學(xué)寫(xiě)作與報(bào)告》（博士生）等。

承擔(dān)的本科生課程：《細(xì)胞生物學(xué)》、《細(xì)胞生物學(xué)實(shí)驗(yàn)》、《航空航天生物醫(yī)學(xué)工程》、《生物醫(yī)學(xué)工程專(zhuān)題》等。

3.科研項(xiàng)目

（1）國(guó)家自然科學(xué)基金面上:應(yīng)力環(huán)境對(duì)磷酸鈣/膠原自組裝分級(jí)結(jié)構(gòu)的影響及機(jī)理研究.項(xiàng)目編號(hào):11272038.執(zhí)行時(shí)間：2013.01-2016.12.

（2）國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目：MGF調(diào)控骨和韌帶組織修復(fù)的力生物學(xué)基礎(chǔ)研究.項(xiàng)目編號(hào):11032012.執(zhí)行時(shí)間：2011.01-2014.12.

（4）國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目：基于乳化-自組裝原理構(gòu)建殼聚糖/聚乳酸兩親刷狀共聚物的新方法研究.項(xiàng)目編號(hào):50803032.執(zhí)行時(shí)間：2009.01-2011.12.

（5）國(guó)家科技支撐計(jì)劃項(xiàng)目：全降解血管支架（金屬鎂基、聚乳酸基）.項(xiàng)目編號(hào)：2012BAI18B01.執(zhí)行時(shí)間:2012.01—2015.12.

（6）中國(guó)博士后科學(xué)基金：納米羥基磷灰石/膠原/聚乳酸/微囊化殼聚糖生物活性骨修復(fù)材料研究.項(xiàng)目編號(hào):20070420330.執(zhí)行時(shí)間：2007.12—2009.03.

4.科研成果

(1)Niu Xufeng, Wang Lizhen, Chen Pin, et al. Emulsion self-assembly synthesis of chitosan/poly(lactic-co-glycolic acid) stimuli-responsive amphiphiles. Macromol. Chem. Phys. 2013, 214(6): 700-706. (SCI: 108LQ; IF2011: 2.361; Q1)

(2)Niu Xufeng, Li Xiaoming, Liu Haifeng, et al. Homogeneous chitosan/poly(L-lactide) composite scaffolds prepared by emulsion freeze-drying. J. Biomat. Sci., Polym. E., 2012, 23(1-4): 391-404. (SCI: 858OI; IF2010: 1.842; Q1)

(3)Niu Xufeng, Fan Yubo, Liu Xinhui, et al. Repair of bone defect in femoral condyle using microencapsulated chitosan, nanohydroxyapatite/collagen and poly(L-lactide)-based microsphere-scaffold delivery system. Artif. Organs. 2011, 35(7): E119-E128. (SCI: 791FU; IF2010: 1.719; Q2)

(4)Liu Haifeng, Li Xiaoming, Niu Xufeng, et al. Improved hemocompatibility and endothelialization of vascular grafts by covalent immobilization of sulfated silk fibroin on poly(lactic-co-glycolic acid) scaffolds. Biomacromolecules, 2011, 12(8): 2914-2924. (SCI: 802CZ; IF2010: 5.325; Q1)

(5)Niu Xufeng, Fan Yubo, Li Ping, Feng Qingling. Biodegradable and bioactive nHAC/CMs/ PLLA scaffolds for bone tissue engineering. Bone, 2010, 47: S438. (SCI: 694EQ; IF2010: 4.601; Q1)

(6)Li Xiaoming, Liu Haifeng, Niu Xufeng, Fan Yubo, Feng Qingling, Cui Fuzhai, Watari Fumio. Osteogenic differentiation of human adipose-derived stem cells induced by osteoinductive calcium phosphate ceramics. J. Biomed. Mater. Res. B 2011, 97B(1): 10-19. (SCI: 735KT; IF2010: 2.22; Q2)

(7)Wang Mingbo, Feng Qingling, Niu Xufeng, et al. A spheres-in-sphere structure for improving protein-loading poly(lactide-co-glycolide) microspheres. Polym. Degrad. Stabil., 2010, 95(1): 6-13. (SCI: 547FA; IF2010: 2.594; Q2)

(8)Niu Xufeng, Feng Qingling, Wang Mingbo, et al. Porous nano-HA/collagen/PLLA scaffold containing chitosan microspheres for controlled delivery of synthetic peptide derived from BMP-2. J. Control. Release, 2009, 134(2): 111-117. (SCI: 423NV; IF2010: 7.164; Q1)

(9)Niu Xufeng, Feng Qingling, Wang Mingbo, et al. In vitro degradation and release behavior of porous poly(lactic acid) scaffolds containing chitosan microspheres as a carrier for BMP-2-derived synthetic peptide. Polym. Degrad. Stabil., 2009, 94(2): 176-182. (SCI: 405HC; IF2010: 2.594; Q2)

(10)Niu Xufeng, Feng Qingling, Wang Mingbo, et al. Preparation and characterization of chitosan microspheres for controlled release of synthetic oligopeptide derived from BMP-2. J. Microencapsul., 2009, 26(4): 297-305. (SCI: 482QN; IF2010: 1.515; Q1)

(11)Tan Rongwei, Niu Xufeng, Gan Shaolei, et al. Preparation and characterization of an injectable composite. J. Mater. Sci. Mater. Med., 2009, 20(6): 1245-1253. (SCI: 442ZY; IF2010: 2.325; Q2)

(12)Niu Xufeng, Luo Yanfeng, Li Yonggang, et al. Design of bioinspired polymeric materials based on poly(D, L-lactic acid) modifications towards improving its cytocompatibility. J. Biomed. Mater. Res., 2008, 84A(4): 908-916. (SCI: 264LB; IF2010: 3.044; Q1)

(13)Niu Xufeng, Wang Yuanliang, Luo Yanfeng, et al. Arg-Gly-Asp (RGD) modified biomimetic polymeric materials. J. Mater. Sci. Technol., 2005, 21(4): 571-576. (IF = 0.869)

(14)Niu Xufeng, Wang Yuanliang, Luo Yanfeng, et al. Synthesis of the biomimetic polymer: aliphatic diamine and RGDS modified poly(D, L-lactic acid). Chinese Chem. Lett., 2005, 16(8): 1035-1038. (IF = 0.488)

(15)Luo Yanfeng, Wang Yuanliang, Niu Xufeng, et al. Evaluation of the cytocompatibility of butanediamine- and RGDS-grafted poly(DL-lactic acid). Eur. Polym. J., 2008, 44(5): 1390- 1402. (IF = 2.143)

(16)Luo Yanfeng, Wang Yuanliang, Niu Xufeng, et al. Synthesis, characterization and biodegradation of butanediamine-grafted poly(DL-lactic acid). Eur. Polym. J., 2007, 43(9): 3856-3864. (IF = 2.143)

(17)Luo Yanfeng, Fu Chunhua, Niu Xufeng, et al. In vitro degradation of butanediamine-grafted poly(DL-lactic acids). J. Wuhan Univ. Technol.-Mater. Sci. Ed., 2007, 22(3): 426-430. (IF = 0.424)

(18)Luo Yanfeng, Wang Yuanliang, Niu Xufeng, et al. Synthesis and characterization of a novel biomaterial: maleic anhydride-modified poly(D, L-lactic acid). Chinese Chem. Lett., 2004, 15(5): 521-524. (IF = 0.488)

(19)牛旭鋒,馮慶玲,王明波等.微囊化殼聚糖/納米羥基磷灰石/膠原/聚乳酸復(fù)合材料.復(fù)合材料學(xué)報(bào),2009,26(2):143-148.

(20)牛旭鋒,王遠(yuǎn)亮,羅彥鳳等.聚（D,L-乳酸）基仿生聚合物材料的合成與表征.功能材料,2006,37(11):1790-1794.(EI收錄)

(21)牛旭鋒,王遠(yuǎn)亮,羅彥鳳等.內(nèi)消旋丙交酯及其聚合物的研究進(jìn)展.高分子材料科學(xué)與工程,2005,21(4):33-36.(EI收錄)

(22)牛旭鋒，樊瑜波，李曉明，周鋼.親水性細(xì)胞外基質(zhì)聚糖/疏水性脂肪族聚酯復(fù)合材料及其制備方法.中國(guó)發(fā)明專(zhuān)利.授權(quán)專(zhuān)利號(hào)：ZL201010142729.4.授權(quán)時(shí)間：2013.01.30.

(23)牛旭鋒、樊瑜波、李曉明、李萍、周鋼、陳品.殼聚糖/脂肪族聚酯兩親接枝共聚物的制備方法.中國(guó)發(fā)明專(zhuān)利.公開(kāi)號(hào):CN102898656A.公開(kāi)時(shí)間:2013.01.30.

(24)樊瑜波，李萍，牛旭鋒，馮利敏，李欣蔚，賈璐.一種剪切力-電聯(lián)合刺激的細(xì)胞培養(yǎng)裝置.中國(guó)發(fā)明專(zhuān)利.公開(kāi)號(hào)：CN101892153A.公開(kāi)時(shí)間：2010.11.24.

(25)馮慶玲，牛旭鋒，崔福齋.具骨誘導(dǎo)因子控釋功能的生物活性骨修復(fù)材料及制備方法.中國(guó)發(fā)明專(zhuān)利.公開(kāi)號(hào)：CN101219241A.公開(kāi)時(shí)間：2008.07.16.