蘭州大學(xué)

姓 名: 齊社寧
Name: She-Ning Qi
職 務(wù)：教授
Duty: Professor
E-mail：qishening@hotmail.com; qishn@lzu.edu.cn

一、科研方向

1、細(xì)胞凋亡與信號轉(zhuǎn)導(dǎo)
2、抗癌藥物藥理學(xué)
3、白血病治療學(xué)
4、神經(jīng)干細(xì)胞
Research Interests
1、Apoptosis and its signal transduction
2、Pharmacology of anti-cancer drugs
3、Therapy of leukemia
4、Neural stem cells

二、榮譽(yù)稱號及獎勵

1、《Fas與白血病的發(fā)生及治療》獲《國外醫(yī)學(xué).臨床生物化學(xué)與檢驗(yàn)學(xué)分冊》優(yōu)秀論文獎。
2、 蘭州大學(xué)“三好研究生”獎。
3、《GP7誘導(dǎo)腫瘤細(xì)胞凋亡的分子傳導(dǎo)機(jī)制研究》獲慶陽市2006年度科技進(jìn)步1等獎。
4、《鬼臼毒類衍生物的抗腫瘤作用和抗氧化作用關(guān)系研究》獲2000-2001年度甘肅省高�？萍汲晒�進(jìn)步獎。
Honors and Awards
1、Excellent Paper Award from the Editorial Board of Foreign Medical Sciences (Section of Clinical Biochemistry and Laboratory Medicine) to the paper “Relationship between Fas and leukemia pathogenesis as well as treatment”.
2、Excellent Doctor Award from Lanzhou University.
3、Award for Advanced Science and Technology from Science and Technology Bureau of Qingyang City to research project “Study on the molecular mechanisms of GP7-induced tumor cell apoptosis”.
4、2000-2001 Year Gansu Higher Education Award for Advanced Science and Technology from Science and Technology Bureau of Gansu Province to research project “Relationship between antitumor effects and antioxidization effects of podophyllotoxin derivatives”.

三、個(gè)人簡歷

1、教育經(jīng)歷
1983.09—1988.07   蘭州醫(yī)學(xué)院臨床醫(yī)學(xué)系學(xué)習(xí),獲學(xué)士學(xué)位畢業(yè)。
1994.09—1998.07   蘭州醫(yī)學(xué)院內(nèi)科（血液病）專業(yè)碩士研究生,獲碩士學(xué)位畢業(yè)。
2002.09—2005.06   蘭州大學(xué)生命科學(xué)學(xué)院博士研究生，獲博士學(xué)位畢業(yè)。
2、 培訓(xùn)經(jīng)歷
1988.07—1989.07   西安醫(yī)科大學(xué)科技英語系學(xué)習(xí),結(jié)業(yè)。
1996.06—1996.07   西安醫(yī)科大學(xué)醫(yī)學(xué)分子生物學(xué)學(xué)習(xí)班學(xué)習(xí)，結(jié)業(yè)。
1999.03—1999.07   中國醫(yī)科大學(xué)衛(wèi)生部日語培訓(xùn)中心學(xué)習(xí)日語，結(jié)業(yè)。
1999.10-1999.12    白求恩醫(yī)科大學(xué)衛(wèi)生部日語培訓(xùn)中心學(xué)習(xí)日語，結(jié)業(yè)。
3、海外留學(xué)經(jīng)歷
2000.04—2001.03   獲笹川醫(yī)學(xué)獎學(xué)金，在日本國福井醫(yī)科大學(xué)留學(xué)。
2004.04—2005.03   獲笹川醫(yī)學(xué)特別獎學(xué)金，在日本國福井大學(xué)醫(yī)學(xué)部留學(xué)。
4、工作經(jīng)歷
1988.07—1994.09   蘭州醫(yī)學(xué)院外語教研室任英語助教。
1994.09—2000.10   蘭州醫(yī)學(xué)院血液病研究所任助理研究員。
2000.10—2002.08   蘭州醫(yī)學(xué)院血液病研究所任副研究員。
2002.08—2004.11   蘭州醫(yī)學(xué)院組織胚胎學(xué)教研室任副研究員,碩士生導(dǎo)師。
2004.11—2008.05   蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院組織胚胎學(xué)教研室任副研究員,主任，碩士生導(dǎo)師。
2008.05—現(xiàn)     在   蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院人體解剖與組織胚胎學(xué)研究所任教授,碩士生導(dǎo)師。
5、兼職
2005.09—現(xiàn)在     蘭州大學(xué)學(xué)報(bào)（醫(yī)學(xué)版）特約英文編輯。
2006.08—現(xiàn)在     蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院人體解剖與組織胚胎學(xué)研究所副所長。
2008.03—現(xiàn)在     平?jīng)鲠t(yī)學(xué)高等�？茖W(xué)校人體解剖與組織胚胎學(xué)專業(yè)客座教授。
Resume
1、 Education Background
?     B.M. (Bachelor of Medicine) in Clinical Medicine, Jul., 1988, Lanzhou Medical College, P. R. China
M.M. (Master of Medicine) in Hematology, Jul., 1998, Lanzhou Medical College, P. R. China
D.Sc. (Doctor in Science) in Zoology, Jun., 2005, Lanzhou University, P. R. China
2、 Training Experience
Oct. -Dec., 1999: Japanese Language Training Course in Baiqiuen Medical University sponsored by Ministry of Health, P. R. China
Mar.-Jul., 1999: Japanese Language Training Course in China Medical University sponsored by Ministry of Health, P. R. China
Jun.-Jul., 1996: Medical Molecular Biology Training Course in Xi’an Medical University sponsored by Department of Biology, Xi’an Medical University
Jul., 1988-Jul., 1989: Medical English Training Course in Xi’an Medical University sponsored by Ministry of Health, P. R. China
3、Overseas Experience
Apr., 2004-Mar., 2005: Senior Visiting Scholar of the First Department of Internal Medicine, Faculty of Medicine, Fukui University, Japan (Sponsored by Sasakawa Medical Special Scholarship)
Apr., 2000-Mar., 2001: Visiting Scholar of the First Department of Internal Medicine, Fukui Medical University, Japan (Sponsored by Sasakawa Medical Scholarship)
4、Professional Experience
May, 2008-Present: Professor, Director, and Tutor of M.M., Department of Histology and Embryology, School of Basic Medicine, Lanzhou University, P. R. China
Nov., 2004-May, 2008: Associate Research Professor, Director, and Tutor of M.M., Department of Histology and Embryology, School of Basic Medicine, Lanzhou University, P. R. China
Aug., 2002-Nov., 2004: Associate Research Professor, and Tutor of M.M., Department of Histology and Embryology, School of Basic Medicine, Lanzhou Medical College, P. R. China
Sep., 1994-Aug., 2002: Researcher Assistant and Associate Research Professor, Institute of Hematology, Lanzhou Medical College, P. R. China
Jul., 1988-Sep., 1994: Teaching Assistant of English, Department of Foreign Languages, Lanzhou Medical College, P. R. China
5、Additional Responsibility
Mar., 2008-Present:  Guest Professor, Pingliang Medical Special High School
Aug.,2006-Present:  Co-Director of the Institute of Anatomy, Histology and Embryology of Lanzhou University
Sep., 2005-Present:  English Language Editor, Journal of Lanzhou University (Medical Sciences)四．發(fā)表論文（Publications）
1、Qi SN, Yoshida A, Wang ZR, Ueda T. GP7 can induce apoptotic DNA fragmentation of human leukemia cells through caspase-3-dependent and -independent pathways. Int J Mol Med. 2004 Jan; 13(1): 163-7. (SCI)
2、Qi SN, Yoshida A, Ueda T. Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells. Int J Oncol. 2003 May; 22(5): 1123-8. (SCI)
3、Qi SN, Jing YX, Dong GX, Chen Y, Yoshida A, Ueda T. GP7 induces internucleosomal DNA fragmentation independent of caspase activation and DNA fragmentation factor in NB4 cells. Oncol Rep.2007 Jul; 18(1): 273-7. (SCI)
4、Qi SN, Zhang ZF, Wang ZY, Yoshida A, Ueda T. L-carnitine inhibits apoptotic DNA fragmentation induced by a new spin-labeled derivative of podophyllotoxin via caspase-3 in Raji cells. Oncol Rep. 2006 Jan; 15(1): 119-22. (SCI)
5、Qi SN, Song LJ, Chen Yan, Jing YX. Reversal of mdr1-mediated multidrug resistance in human leukemia cells by a new spin-labeled derivative of podophyllotoxin. Pharmazie. doi: 10.1691/ph.2010.9717. (SCI)
6、Kang H, Bao GJ, Qi SN (corresponding author). Biomechanical responses of human temporomandibular joint disc under tension and compression. Int J Oral Maxillofac Surg. 2006 Sep; 35(9): 817-21. (SCI)
7、Qi SN, Chen C. An experimental study on etoposide-induced NB4 cell apoptosis. Journal of Gansu Sciences 13(4): 94-6, Dec, 2001.
8、Qi SN, Wan SM, Li XY, Li WG, Wang J. 4-〔4″-(2″, 2″, 6″, 6″- Tetramethyl -1″- piperidinyloxy)amino〕-4′-demethylepipodophyllotoxin inducing NB4 cell apoptosis. Chinese Journal of Pharmacology and Toxicology 14(1): 62-4, Feb, 2000.
9、Mu LP, Qi SN, Lu L, Yao XJ. Clinical significance of quantitative AgNOR analysis in bone marrow cells of acute leukemia. Journal of Lanzhou Medical College 23(1): 54-5, Mar, 1997.
10、Mu LP, Qi SN. Analysis of pathogenesis and transformation of MDS subtypes in 121 cases. Foreign Medical Sciences (Section of Clinical Biochemistry and Laboratory Medicine) 17(suppl): 254-6, Aug, 1996.
11、Ma RS, Bai DC, Qi SN, Jiang XC, Liu BJ. Effects of blood hyperviscosity on contents and ultrastructure of mitochondria of cerebral cells in mice. Chinese Journal of Anatomy 29(6): 747-50, Dec, 2006.
12、Ma RS, Bai DC, Jiang XC, Pan AY, Qi SN. Correlation of free calcium concentration in mouse cerebral cells with blood hyperviscosity. Chinese Journal of Clinical Rehabilitation 8 (4)：648-9, Feb, 2004.
13、Qi SN. VP16-induced apoptosis. Journal of Lanzhou Medical College 24(3): 67-9, Sep, 1998.
Qi SN, Zhang QM. Effects of selenium on ion homeostasis and transparency in cultured lenses. Foreign Medical Sciences (Section of Medgeography) 1：13-5, Jan, 1990.
14、Qi SN. Introduction of International Council of Scientific Unions (ICSU). Trends of Resources & Ecological Environment Network Research 2: 36, Jun, 1990.
15、Qi SN, Mu LP. Fas and viral infection. In: Chinese Medicine Digest (Section of Experimental Medicine and Clinics) (2nd part). Ma D, Zhang L, Hu XM (ed). Chengdu Science and Technology University Publishing House, Chengdu, pp407-8, Mar, 1997.
16、Qi SN, Wang J. An experimental study on GP7-induced Raji cell apoptosis. Chinese Pharmacological Bulletin 15(2): 187-8, Apr, 1999.
17、Qi SN, Li XY, Yang TM. GP7- and etoposide-induced apoptosis of hematopoietic malignant tumor cells. Chinese Journal of Integrated Traditional and Western Medicine 20(suppl): 73－4, Jul, 2000.
18、Qi SN, Yang TM, Wan SM, Li XY, Wang J. An experimental study on VP16-induced Raji cells apoptosis. Journal of Lanzhou Medical College 25(3): 1-2, Sep, 1999.
19、Chen Y, Qi SN (corresponding author). Effects of 4-[4''-(2'', 2'', 6'', 6''-tetramethyl-l''- piperidinyloxy)-amino]-4'-demethyl-epipodophyllotoxin on K562/ADM cells. Chinese Journal of Pharmacology and Toxicology 21(2): 107-12, Apr, 2007.
20、Liu TY, Zhang WW, Dong S, Qi SN (corresponding author). CT evaluation of peripheral main vessel invasion in central pulmonary carcinoma. Journal of Lanzhou University (Medical Sciences) 34(3): 33-4, Sep, 2008.
21、Li XY, Qi SN, Xu FT. An experimental study on the regulatory effects of interleukin-3 on umbilical cord blood stromal cells. Journal of Lanzhou Medical College 24(4): 4-6, Dec, 1998.
22、Mu LP, Qi SN, Zeng F, Yao XJ, Li FP. A quantitative pathological analysis on 65 bone marrow tissue sections. Chinese Journal of Clinical and Experimental Pathology 13(3): 235-7, Aug, 1997.
23、Yang YJ, Qi SN, Li HQ. Observation on the therapeutic effects of CBS, MET and AMO in the treatment of chronic gastric diseases with HP positive. Journal of Modern Digestive diseases and Endoscopy 2(1): 81-2, Jan, 1997.
24、Ma RS, Qi SN, Jiang XC. Exploration of the One-Teacher-Responsibility Teaching Model. Researches in Medical Education 5(9): 817-8, Sep, 2006.
25、Mu LP, Pei XY, Liu ZG, Qi SN. Study on megakaryoblastic leukemia in 12 cases. Journal of Lanzhou Medical College 22(4): 65-7, Dec, 1996.
26、Qi SN, Mu LP. Relationship between Fas and leukemia pathogenesis as well as treatment. Foreign Medical Sciences (Section of Clinical Biochemistry and Laboratory Medicine) 18(suppl): 105-6, Jul, 1997.
27Zhang ZF, Qi SN(corresponding author). Idarubicin-induced apoptosis. Journal of Modern Oncology 12 (5)：480-2, Oct, 2004.
28、Qi SN. Training on tumor surgeons. Foreign Medical Sciences (Section of Medical Education) 12(1): 48, Jan, 1991.
29、Qi SN. DNA sequencing and PCR techniques. In: Medical Molecular Biology. Li XY (ed). Lanzhou University Publishing House, Lanzhou, pp87-107, Jun, 1999.
30、Zhao CL, Zhao L, Wan L, Qi SN (corresponding author). Culture and identification of human preadipocytes. Journal of Lanzhou University (Medical Sciences) 33(3): 8-11, Sep, 2007.

五、學(xué)術(shù)團(tuán)隊(duì)

姜信誠 馬瑞生 周中平 謝坤 劉秉鈞 楊婧 陳焱 景原雪 宋麗娟