北京大學

黃 健: 博士，副教授  

E-Mail  jhuang@bjmu.edu.cn

地址北京市海淀區(qū)學院路38號藥學院306室   郵編100191

1995 年畢業(yè)于蘭州大學，獲理學學士學位；

1998年畢業(yè)于蘭州大學，獲理學碩士學位；

2005年畢業(yè)于北京大學，獲藥物化學博士學位；

2005年至今在北京大學藥學院化學生物學系無機化學專業(yè)。

研究方向：細胞無機化學和無機藥物化學；研究骨質疏松的發(fā)病機制和藥物預防；研究藥物對前列腺癌骨轉移的抑制。

近幾年發(fā)表文章:

1.王芃, 黃健*, 張?zhí)焖{, 王夔*.氯化鑭抑制人轉移型雄性激素非依賴性前列腺癌細胞DU145的生長和遷移. 科學通報，2010, 55(23): 2289-2295.

2.Jian huang, Xi. Wang, Tian-lan Zhang, Kui Wang. Alterations of ovariectomized rat bone and impact of non-collagenous proteins on mineralization. Joint Bone Spine, 2009, 76(2):176-183 

3.Shi Yanling, Wang Liwen, Huang Jian, Gou Baodi, Zhang Tianlan, Wang Kui. Lanthanum Suppresses Osteoblastic Differentiation Via Pertussis Toxin-Sensitive G Protein Signaling in Rat Vascular Smooth Muscle Cells. Journal of Cellular Biochemistry 2009, 108: 1184-1191

4.Wang Chen-Guang, Liao Jia-Wang, Gou Bao-Di, Huang Jian, Tang Rui-Kang, Tao Jin-Hui,  Zhang Tian-Lan, Wang Kui. Crystallization at Multiple Sites inside Particles of Amorphous Calcium Phosphate. Crystal Growth Design, 2009, 9: 2620–2626.

5.Xi Wang, Jian Huang*, Tianlan Zhang , Kui Wang. Cytoskeleton reorganization and FAK phosphorylation are involved in lanthanum (III)-promoted proliferation and differentiation in rat osteoblasts. Progress in Nature Science 

2009,19: 331-335 

6.Xi Wang, Lan Yuan, Jian Huang*, Tian-Lan Zhang*, Kui Wang. Lanthanum Enhances in vitro Osteoblast Differentiation via Pertussis Toxin-sensitive Gi Protein and ERK Signaling Pathway. Journal of Cellular Biochemistry 2008, 105: 1307-1315 

7.王熙, 黃健*, 張?zhí)焖{, 王夔. La3 + 通過重組細胞骨架影響大鼠成骨細胞增殖、分化, 自然科學進展, 2008, 18: 1053-1057 

8.Jian huang, Lan Yuan, Xi. Wang, Tian-lan Zhang, Kui Wang. Icarin and its glycosides enhance osteoblastic ,but suppress osteoclastic, differentiation and activity in vitro. Life Sciences,  2007,81(10):832-840

9.Jian Huang, Jina-Chao Zhang, Tian-Lan Zhang, Kui Wang. Icariin suppresses bone resorption activity of rabbit osteoclasts in vitro. Chinese Science Bulletin, 2007, 52(7):890-895. ‘

10.Jian Huang, Tian-Lan Zhang, Shan-jin Xu, Kui Wang, Jing Zhang, Ya-Ning Xie.. Effects of Lanthanum on Composition, Crystal Size and Lattice Structure of Femur Bone Mineral of Wistar Rats. Calcif Tissue Int， 2006 78（4）:241–247

11.黃健, 張金超,張?zhí)焖{, 許善錦,王夔. 淫羊霍苷對破骨細胞骨吸收功能的影響及其作用機制研究. 科學通報,  2006, 51(24):2851-2856