武漢理工大學(xué)

姓 名

殷義霞

性 別

女

民 族

漢

出生年月

1978年7月        

職  稱

副研究員

職 務(wù)

／      

聯(lián)系電話

單位名稱

材料復(fù)合新技術(shù)國家重點(diǎn)實(shí)驗(yàn)室

Email

yinyixia@whut.edu.cn

實(shí)驗(yàn)室網(wǎng)址

／

研究方向

生物醫(yī)用材料 生物醫(yī)學(xué)工程 干細(xì)胞與組織工程

教育背景

 

工作經(jīng)歷

2007/01-至今，美國哈佛大學(xué)醫(yī)學(xué)院，訪學(xué), 合作導(dǎo)師：Ali Khademosseini, Joseph Bonventre

2014/07-至今，武漢理工大學(xué)，材料復(fù)合新技術(shù)國家重點(diǎn)實(shí)驗(yàn)室，副研究員

2012/02-2014/06，武漢理工大學(xué)，生物材料工程研究中心，助理研究員

 

項(xiàng)目情況

1. 國家自然科學(xué)基金青年基金： PDLLA/PRGD/β-TCP神經(jīng)修復(fù)材料抑制神經(jīng)瘤形成的作用機(jī)制（No.51403168），項(xiàng)目起止時(shí)間：2015.01-2017.12.（主持）

2. 含銀藻酸鹽敷料的安全性研究與評(píng)估, 企業(yè)委托項(xiàng)目，起止時(shí)間：2016.04-2018.04. （主持）

3. 國家重點(diǎn)實(shí)驗(yàn)室基金：基于重建神經(jīng)再生微環(huán)境的誘導(dǎo)型修復(fù)材料（No.47182007）(2018.3-2020.12) （主持）

4. 誘導(dǎo)型納米復(fù)合神經(jīng)移植物研發(fā), 國家重大發(fā)展與研究項(xiàng)目“135” (2016YFC1101605)，2016.09-2020.12.（項(xiàng)目骨干）

5. 適用于骨與關(guān)節(jié)個(gè)性化植入假體增彩制造生物醫(yī)用材料的研制，國家重大發(fā)展與研究項(xiàng)目“135”（2016YFC1101302），項(xiàng)目起止時(shí)間： 2016.07-2020.06. （項(xiàng)目骨干）

 

代表性學(xué)術(shù)
成果

1） Jiling Yi, Nan Jiang, Binbin Li, Qiongjiao Yan, Tong Qiu, K. Swaminathan Iyer, Yixia Yin*, Honglian Dai, Ali K. Yetisen, Shipu Li. Painful Terminal Neuroma Prevention by Capping PRGD/PDLLA Conduit in Rat Sciatic Nerves. Advanced Science.2018. DOI: 10.1002/advs.201700876.

2） Nan Jiang, Yong Wang, YiXia Yin*, Ruipeng Wei, Guoliang Ying, Binbin Li, Tong Qiu, Patrick Rijn, Ge Tian, Qiongjiao Yan, Honglian Dai, Henk J Busscher, Shipu Li, Ali K Yetisen, XiaoYu Yang. bFGF and Poly-RGD Cooperatively Establish Biointerface for Stem Cell Adhesion, Proliferation and Differentiation. Advanced Materials Interfaces. 2018.Doi: DOI: 10.1002/admi.201700702.

3） Jiling Yi, Feng Xiong, Binbin Li, Heping Chen, Yixia Yin*, Honglian Dai, Shipu Li. Degradation characteristics, cell viability andhost tissue responses of PDLLA-based scaffold with PRGD and β-TCP nanoparticles incorporation. Regenerative Biomaterials, 2016:1-8.

4） Yixia Yin, Binbin Li, Qiongjiao Yan, Honglian Dai, Shipu Li*. Promotion of peripheral nerve regeneration and prevention of neuroma formation by PRGD/PDLLA/β-TCP conduit: report of two cases [J]. Regenerative Biomaterials, 2015, 2: 119-124.

5） Yixia Yin, Jiling Yi, Lijuan Xie, Qiongjiao Yan, Honglian Dai, Shipu Li*. Synthesis, characterization and biological evaluation of poly [LA-co-(Glc-alt-Lys)] for nerve regeneration scaffold [J]. Frontiers of Materials Science. 2014, 8: 95-101.

6） Yixia Yin, Lin Qiang, Sun Haiming, Chen Dan, Wu Qingzhi, Chen Xiaohui, Li Shipu. Effects of ZnO hierarchical architectures on RSC96 Schwann cells [J]. Nanoscale Research Letters. 2012, 7:439-441.

7） Jie Zeng#, Yixia Yin#, Li Zhang, Wanghui Hu, Chaocan Zhang, Wanyu Chen. A Supramolecular Gel Approach to Minimize the Neural Cell Damage during Cryopreservation Process [J]. Macromolecular Bioscience.2015, DOI: 10.1002 /mabi. 201500277. (#: Co-first author)

8） Tong Qiu, Yixia Yin*, Binbin Li, Lijuan Xie, Qiongjiao Yan, Honglian Dai, Xinyu Wang, Shipu Li. PDLLA/PRGD/β-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration [J]. Journal of Biomedical Materials Research A. 2014, 102: 3734-3743.

9） Binbin Li, Tong Qiu, Ping Zhang, Xinyu Wang, Yixia Yin* and Shipu Li. IKVAV regulates ERK1/2 and Akt signaling pathways on BMMSCs growth and proliferation [J]. Cell Proliferation. 2014, 47:133-145.

10） Fang Liu, Haiwei Zhang, Kaiming Zhang, Yixia Yin*, Shipu Li. Rapamycin promotes Schwann cell migration and nerve growth factor secretion [J]. Neural Regeneration Research. 2014, 9(6):602-609.

 (*：corresponding author )

軍隊(duì)科學(xué)技術(shù)獎(jiǎng)二等獎(jiǎng)：誘導(dǎo)周圍神經(jīng)再生的可降解材料研制及臨床應(yīng)用。

授權(quán)專利情況： 

一種緩釋型透明質(zhì)酸基可注射行水凝膠及其制備方法（專利號(hào)：    201810233185.9）。