中國藥科大學(xué)

陸續(xù)，博士，碩士研究生導(dǎo)師。2013年6月畢業(yè)于上海交通大學(xué)植物學(xué)專業(yè)，獲理學(xué)博士學(xué)位，論文獲選為2015年度上海市優(yōu)秀博士學(xué)位論文。主要從事生藥活性成分與生物技術(shù)方面的研究。作為課題負(fù)責(zé)人，先后主持國家自然科學(xué)基金、江蘇省自然科學(xué)基金、南京大學(xué)生物醫(yī)藥國家重點(diǎn)實(shí)驗(yàn)室開放研究基金等。迄今已在New Phytologist, Molecular Plant, PLoS ONE, Industrial Crops and Products等雜志發(fā)表研究論文20余篇，獲授權(quán)國家發(fā)明專利4項(xiàng)。

研究方向：

1.藥用植物次生代謝調(diào)控和萜類生物合成

2.藥用植物分子生物學(xué)

3.藥用植物代謝組學(xué)

目前承擔(dān)課題情況：

1.國家自然科學(xué)基金項(xiàng)目名稱：銀杏內(nèi)酯生物合成途徑相關(guān)P450基因的克隆與功能研究；項(xiàng)目批準(zhǔn)號：81403043；項(xiàng)目起止年月：2015.1-2017.12；

2.江蘇省自然科學(xué)基金項(xiàng)目名稱：AP2/ERF類轉(zhuǎn)錄因子在三七三萜皂苷生物合成途徑中的調(diào)控機(jī)制研究；項(xiàng)目批準(zhǔn)號：BK20140663；項(xiàng)目起止年月：2014.7-2016.6；

3.中國藥科大學(xué)科研啟動基金項(xiàng)目名稱：銀杏內(nèi)酯合成途徑關(guān)鍵基因的表達(dá)研究；項(xiàng)目批準(zhǔn)號：ZJ14115；項(xiàng)目起止年月：2014.1-2015.12。

研究成果

1.代表性論文（*為通訊作者）

1)Xu Lu, Ling Zhang, Fangyuan Zhang,Weimin Jiang, Qian Shen, Lida Zhang, Zongyou Lv, GuofengWang, Kexuan Tang*. 2013. AaORA, a trichome-specific AP2/ERF transcription factor of artemisia annua, is a positive regulator in the biosynthesis of artemisinin and disease resistance to Botrytis cinerea. New Phytologist.198(4): 1191-202.

2)Xu Lu, Weimin Jiang, Ling Zhang, Fei Zhang, Fangyuan Zhang, Qian Shen, Guofeng Wang, Kexuan Tang*. 2013. AaERF1 positively regulates the resistance to B. cinerea in Artemisia annua. PLoS One. 8(2): e57657.

3)Xu Lu, Qian Shen, Ling Zhang, Fangyuan Zhang, Weimin Jiang, Zongyou Lv, Tingxiang Yan, Xueqing Fu, Guofeng Wang, Kexuan Tang*. 2013. Promotion of artemisinin biosynthesis in transgenic Artemisia annua by overexpressing ADS, CYP71AV1 and CPR genes. Industrial Crops and Products. 49: 380-385.

4)Xu Lu,  Fangyuan Zhang, Qian Shen ,Weimin Jiang, Qifang Pan, Zongyou Lv, Tingxiang Yan, Xueqing Fu, Yuliang Wang, Hongmei Qian, Kexuan Tang*. 2014. Overexpression of Allene Oxide Cyclase Improves the Biosynthesis of Artemisinin in Artemisia annua L. PLoS One. 9(3): e91741.

5)Xu Lu, Xiuyan Lin, Qian Shen, Fangyuan Zhang, Yueyue Wang, Yunfei Chen, Tao Wang, Shaoyan Wu, Kexuan Tang*. 2011. Characterization of the Jasmonate Biosynthetic Gene Allene Oxide Cyclase in Artemisia annua L., Source of the Antimalarial Drug Artemisinin. Plant Molecular Biology Reporter. 29: 489-497.

6)Xu Lu, Weimin Jiang, Ling Zhang, Fangyuan Zhang, Qian Shen, Tao Wang, Yunfei Chen, Shaoyan Wu, Zongyou Lv, Erdi Gao, Bo Qiu, Kexuan Tang*. 2012. Characterization of a novel ERF transcription factorin Artemisia annua and its induction kinetics after hormones and stress treatments. Molecular Biology Reports. 39(10): 9521-9527.

7)Xu Lu, Fangyuan Zhang, Weimin Jiang, Xiuyan Lin, Yunfei Chen, Qian Shen, Tao Wang, Shaoyan Wu, Xiaofen Sun, Kexuan Tang*. 2012. Characterization of the first specific jasmonate biosynthetic pathway gene allene oxide synthase from Artemisia annua. Molecular Biology Reports. 39(3): 2267-2274.

8)Xu Lu, Wei Zhou , Feng Gao*. 2010. Localization of 45S rDNA and DFR gene of Citrus sinensis Osbeck cv. Ruby. Biologia Plantarum. 54 (4): 798-800.

9)Xu Lu, Wei Zhou, Feng Gao*. 2009. Cloning, characterization and localization of CHS gene from blood orange, Citrus sinensis (L.) Osbeck cv. Ruby. Molecular Biology Reports. 36(7): 1983-90.

10)Weimin Jiang1, Xu Lu1, Bo Qiu, Fangyuan Zhang, Qian Shen, Zongyou Lv, Xueqing Fu, Tingxiang Yan, Erdi Gao, Mengmeng Zhu, Lingxian Chen, Ling Zhang, Guofeng Wang, Xiaofen Sun, Kexuan Tang*. 2014. Molecular Cloning and Characterization of a Trichome-Specific Promoter of Artemisinic Aldehyde Δ11(13) Reductase (DBR2) in Artemisia annua. Plant Molecular Biology Reporter. 32: 82-91.

2.專利

1)青蒿AaORA蛋白及編碼基因、轉(zhuǎn)基因青蒿植株的獲得方法.唐克軒，陸續(xù)，江偉民，張凌，張利達(dá)，張芳源，沈乾，呂宗友,高爾娣.ZL201210014227.2.已授權(quán)。

2）AaORA基因啟動子及其用途.唐克軒，陸續(xù)，張芳源，沈乾，張凌，江偉民，呂宗友.ZL201210384850.7.已授權(quán)。

3）采用水培技術(shù)快速繁殖轉(zhuǎn)基因青蒿的方法,唐克軒,陸續(xù),張凌,吳韶龑,江偉民,張芳源,沈乾.ZL201110340421.5.已授權(quán)。

4)轉(zhuǎn)DBR2基因提高青蒿中青蒿素含量的方法.唐克軒,沈乾,陳韻斐,王濤,吳韶龑,陸續(xù).ZL201210014227.2.已授權(quán)。

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