中國藥科大學(xué)

胡慶華，男，副教授，中國藥科大學(xué)藥理教研室。2002-2006年在南京大學(xué)匡亞明學(xué)院基礎(chǔ)學(xué)科教學(xué)強化部學(xué)習(xí)獲學(xué)士學(xué)位；2006-2011年在南京大學(xué)碩博連讀并獲博士學(xué)位，研究方向為代謝性疾病藥理。目前主持國家自然科學(xué)基金青年項目1項（NSFC81202573）和中央高校基本科研業(yè)務(wù)業(yè)務(wù)費培育項目1項，參與國家自然科學(xué)基金項目1項（NSCF81373419），曾參與國家杰出青年項目1項（NSFC81025025）、國家自然科學(xué)基金（NSFC81025025，NSFC30873413）和江蘇省自然科學(xué)基金（BK2010365，BK2007143）各2項，作為參研人員參與數(shù)項科研及新藥前期研究項目。截至目前，已發(fā)表中、英文學(xué)術(shù)論文共篇18篇（SCI收錄13篇，EI收錄1篇，國內(nèi)核心期刊4篇），其中第一作者或通訊作者論文12篇；作為第三發(fā)明人申請發(fā)明專利1項并獲得授權(quán)。

電話：13770837347,EMAIL：huqh@cpu.edu.cn

·Hu, Q. H., Wei, B., Wei, L., Hua, K., Yu, X., Li, H., Ji, H. Sodium tanshinone IIA sulfonate ameliorates ischemia-induced myocardial inflammation and lipid accumulation in Beagle dogs through NLRP3 inflammasome. Int J Cardiol 196, 183-192 (2015).
·Li, Q., Hu, Q. H., Wang, X., Zong, Y., Zhao, L., Xing, J., Zhou, J., Zhang, H. Discovery of Novel 2-(piperidin-4-yl)-1H-benzo[d]imidazole Derivatives as Potential Anti-Inflammatory Agents. Chem Biol Drug Des [Epub ahead of print] (2015). (共同一作)
·Hu, Q. H., Zhu, J. X., Ji, J., Wei, L. L., Miao, M. X., Ji, H. Fructus Gardenia Extract ameliorates oxonate-induced hyperuricemia with renal dysfunction in mice by regulating organic ion transporters and mOIT3. Molecules 18 (8), 8976-8993 (2013).
·Xu, Y. Y., Li, S. N., Yu, G. J., Hu, Q. H., Li, H. Q. Discovery of novel 4-anilinoquinazoline derivatives as potent inhibitors of epidermal growth factor receptor with antitumor activity. Bioorg Med Chem, 21, 6084-6091 (2013). (通訊作者)
·Chen, Y. S., Hu, Q. H., Zhang, X., Kong, L. D. Beneficial effect of rutin on oxonate-induced hyperuricemia and renal dysfunction in mice. Pharmacology 92, 75-83 (2013). (共同一作)
·Hu, Q. H., Zhang, X., Pan, Y., Li, Y. C., Kong, L. D. Allopurinol, rutin, and quercetin ameliorate NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats. Biochem pharmacol 84 (1), 113-125 (2012).
·Hu, Q.H., Zhang, X., Wang, X., Jiao, R. Q., Kong, L. D. Quercetin regulates the expression of organic ion transporters and uromodulin and reduces renal damage in hyperuricemic mice. Eur J Nutr 51 (5), 593-606(2012).
·Hu, Q. H., Wang, C., Li, J. M., Zhang, D. M., Kong, L. D. Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement. Am J Physiol Renal Physiol 297 (4), 1080-1091 (2009).
·Hu, Q.H., Jiao, R. Q., Wang, X., Lv, Y. Z., Kong, L. D. Simiao pill ameliorates urate underexcretion and renal dysfunction in hyperuricemic mice. J Ethnopharmacol 128 (3), 685-692 (2010).
·Hu, Q. H., Zhang, X., Wang, X., Kong, L. D. Magiferin promotes uric acid excretion and kidney function improvement and modulates related renal transporters in hyperuicemic mice.Acta Pharmaceutica Sinica 45 (10), 1239-1247 (2010).
·胡慶華, 繆明星, 盧國, 季暉. 槲皮素對尿酸性腎病大鼠腎臟NLRP3和TLRs表達(dá)的影響. 中草藥 44 (24), 3496-3502 (2013).
·胡慶華, 朱繼孝, 李寧, 繆明星. 梔子苷對氧嗪酸鉀鹽致小鼠高尿酸血癥的作用及其機制研究. 中南藥學(xué) 11 (10), 721-725 (2013).
·Li, J. M., Li, Y. C., Kong, L. D., Hu, Q. H. Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats. Hepatology51 (5), 1555-1566 (2010).
·Li, J. M., Wang, W., Fan, CF., Wang, MX., Zhang, X., Hu, Q. H., Kong, L. D. Quercetin preserves ß-cell mass and function in fructose-induced Hyperinsulinemia through modulating Pancreatic Akt/FoxO1 Activation. Evid Based Complement Alternat Med 2013, 303902. (2013).   
·Wang, X., Wang, C. P., Hu, Q. H., Lv, Y. Z., Zhang, X., Ouyang, Z., Kong, L. D. The dual actions of Sanmiao wan as a hypouricemic agent: down-regulation of hepatic XOD and renal mURAT1 in hyperuricemic mice. J Ethnopharmacol128 (1), 107-115 (2010).
·Mo, S. F., Zhou, F., Lv, Y. Z., Hu, Q. H., Zhang, D. M., Kong, L. D. Hypouricemic action of selected flavonoids in mice: structure-activity relationships.Biol Pharm Bull30 (8), 1551-1556 (2007). 
·呂耀中, 胡慶華, 王星, 歐陽臻, 孔令東. 二妙丸水提取物對高尿酸血癥小鼠尿酸失衡及其相關(guān)基因和蛋白水平的影響. 中草藥 3, 418-423 (2010).
·李建梅, 王闖, 胡慶華, 孔令東. 果糖引起大鼠瘦素功能失調(diào)及槲皮素和蘆丁的改善作用. 中國天然藥物 6, 466-473 (2010).
·孔令東, 潘穎, 胡慶華等. CN200710190133.X 槐米黃酮提取物在制備尿酸轉(zhuǎn)運子URAT1抑制藥物中的應(yīng)用.