中國藥科大學

邢磊，男，博士，講師，碩士研究生導師。2005年畢業(yè)于河南大學藥學院藥物制劑專業(yè)，2005~2008年在河南大學藥學院攻讀藥劑學碩士學位，其中2006.7~2008.5期間在軍事醫(yī)學科學院金義光課題組從事自組裝藥物傳遞系統(tǒng)的研究；2008年考入上海交通大學化學化工學院，師從車順愛教授，研究方向為pH響應性配位聚合物用于藥物傳遞的研究，主要參與《國家973項目--納米結構材料的程序化組裝》和《重大新型藥物開發(fā)項目》。2012年9月加入中國藥科大學藥學院藥劑教研室從事教學科研工作。目前已在SCI期刊上發(fā)表較高水平論文13篇。主持和參與的國家自然科學基金6項，江蘇省自然基金3項。主持國重優(yōu)秀青年人才基金1項。

研究方向：藥用高分子材料與靶向釋藥系統(tǒng)研究；配位藥物遞送系統(tǒng)研究；聚合物藥物遞送系統(tǒng)研究

近期發(fā)表的文章：

1. Zhang BF†, Xing L†, Cui PF, Wang FZ, Xie RL, Zhang JL, Zhang M, He YJ, Lyu JY, Qiao JB, Chen BA, Jiang HL*. Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine. Biomaterials. 2015, 61: 178-189. (†equal contribution)

2. Kim YK†, Zhang M†, Zhang BF, Wang FZ, Cui PF, Xie RL, Xing L*, and Jiang HL*. Hepatic Targeting Gene Delivery Using Galactosylated Ester-Based Polyspermine. J. Nanosci. Nanotechnol. 2015, doi:10.1166/jnn.2015.11341.

3. Kim YK†, Xing L†, Chen BA, Xu FG, Jiang HL*, Zhang C*. Aerosol delivery of programmed cell death protein 4 using polysorbitol-based gene delivery system for lung cancer therapy. J. Drug Target. 2014, 22(9): 829-838. (†equal contribution)

4. Xie RL†, Jang YJ†, Xing L, Zhang BF, Wang FZ, Cui PF, Cho MH*, Jiang HL*. A novel potential biocompatible hyperbranched polyspermine for efficient lung cancer gene therapy. Int. J. Pharm. 2014, 478(1): 19-30.

5. Su Z†, Xing L†, Chen Y, Xu Y, Yang F, Zhang C, Ping Q, Xiao Y*. Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas. Mol. Pharm. 2014, 11(6): 1823-34. (†equal contribution)

6. Zheng H., Xing L, Cao Y, and Che S*, Coordination bonding based pH-responsive drug delivery systems, Coordin. Chem. Rev. 2013, 257: 1933-1944.

7. Xing L, Zheng H, Cao Y, Che S*, Coordination Polymer Coated Mesoporous Silica Nanoparticles for pH-Responsive Drug Release, Adv. Mater. 2012. 24: 6433-6437.

8.  Xing L, Cao Y, Che S*, Synthesis of Core-Shell Coordination Polymer Nanoparticles (CPNs) for pH-responsive Controlled Drug Release, Chem. Commun. 2012. 48: 5995-5997.

9. Xing L, Zheng H, Che S*, A pH-responsive Cleavage Route Based On a Metal-Organic Coordination Bonding, Chem. Eur. J. 2011, 17: 7271-7275.

10. Gao C†, Zheng H†, Xing L†, Shu M and Che S*, Designable Coordination Bonding in Mesopores as a pH-Responsive Release System, Chem. Mater. 2010, 22: 5437-5444. (†equal contribution)

11. Li C, Xing L and Che S*, Coordination Bonding Based pH-Responsive Albumin Nanoparticles for Anticancer Drug Delivery, Dalton T. 2012, 41: 3714-3719.

12. Ma Y, Xing L, Zheng H and Che S*, Anionic-Cationic Switchable Amphoteric Monodisperse Mesoporous Silica Nanoparticles, Langmuir, 2011, 27: 517-520.

13. Jin Y*, Xing L, Tian Y, Li M, Gao C, Du L, Dong J* and Chen H, Self-assembled drug delivery systems. Part 4. In vitro/in vivo studies of the self-assemblies of cholesteryl-phosphonyl zidovudine. Int. J. Pharm. 2009, 345: 40-48.

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